Glossary



Programs and tools

Term Definition References/Links
AUGUSTUS AUGUSTUS is an ab initio gene predictor for eukaryotic assemblies. https://doi.org/10.1093/nar/gkl200
https://doi.org/10.1093/nar/gki458
BLAST BLAST (Basic Local Alignment Search Tool) is a tool for finding regions of similarity between biological sequences using gene alignment. https://blast.ncbi.nlm.nih.gov/Blast.cgi
BUSCO BUSCO (Benchmarking Universal Single Copy Orthologs) is a tool for measuring genome completeness. It charts a genome assembly against a database of known single-copy orthologs found in all organisms of a given clade, and determines completeness depending on how many are present. https://busco.ezlab.org/
https://doi.org/10.1093/bioinformatics/btv351
BuscoPhylo BuscoPhylo is a freely accessible tool for the easy phylogenetic analysis of genome sequences using BUSCO. BuscoPhylo runs BUSCO to identify common universal orthologues between sequences, then performs a phylogenetic analysis on those orthologues. https://buscophylo.inra.org.ma/
https://doi.org/10.1038/s41598-022-22461-0
KEGG KEGG (Kyoto Encyclopedia of Genes and Genomes) is a database and a collection of annotation tools used to represent and predict biological systems, such as metabolic pathways. https://doi.org/10.1093/nar/28.1.27
https://doi.org/10.1002/pro.3715
https://doi.org/10.1093/nar/gkac963
RepeatMasker RepeatMasker is a program that screens DNA sequences for interspersed repeats and low complexity DNA sequences.
(Description from repeatmasker.org)
http://www.repeatmasker.org/
RepeatModeler RepeatModeler is a de novo transposable element (TE) family identification and modeling package. At the heart of RepeatModeler are three de-novo repeat finding programs ( RECON, RepeatScout and LtrHarvest/Ltr_retriever ) which employ complementary computational methods for identifying repeat element boundaries and family relationships from sequence data.
(Description from repeatmasker.org/RepeatModeler).
https://doi.org/10.1073/pnas.1921046117
eggNOG eggNOG (evolutionary geneology of genes: Non-supervised Orthologous Groups) is a public database of gene orthologues, evolutionary histories, and functiona annotations. eggNOG can be used to provide functional annotation to gene sequences based on gene orthology. https://eggnog5.embl.de/
https://doi.org/10.1093/nar/gky1085